Confirmation
Many presentations are diagnosed clinically, but testing or biopsy may be appropriate when morphology is atypical, the differential remains consequential, or response is unexpected.
Treatment reasoning
Management depends on site, extent, severity, symptoms, comorbidities, prior response, patient goals, and safety considerations. Learn the framework—what, why, when, risk, monitoring, and comparison—rather than a detached drug list. Current systemic and targeted treatment decisions require guideline, labeling, population, and monitoring review.
Population context
Age, pregnancy or lactation, immune status, comorbidities, organ function, access, and phenotype can change evaluation and management. Do not generalize one population’s evidence to every learner scenario.